Description

(2S)-Tetrahydro-2-Furanmethanamine Hydrochloride CAS NO 21801-94-5 is a high-purity chiral amine derivative, specifically the hydrochloride salt of (S)-2-(Aminomethyl)tetrahydrofuran. This compound matters as a critical chiral building block and intermediate in the synthesis of complex pharmaceutical molecules, offering precise stereochemical control. It is primarily needed by research institutions and manufacturers in the pharmaceutical and agrochemical industries for developing active pharmaceutical ingredients (APIs) and other fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the asymmetric synthesis of various drug candidates, particularly for central nervous system (CNS) and antiviral applications.
• Agrochemical Synthesis: Used in the research and development of chiral pesticides and herbicides where specific stereochemistry is required for biological activity.
• Ligand Precursor: Serves as a starting material for the preparation of chiral ligands used in asymmetric catalysis and metal complexation.
• Fine Chemical Production: Employed in the manufacture of other specialty chemicals requiring the (S)-2-(aminomethyl)tetrahydrofuran scaffold.
• Academic & Industrial Research: A valuable reagent for methodological development in organic synthesis and medicinal chemistry research programs.

Basic Information

Product Name	(2S)-Tetrahydro-2-Furanmethanamine Hydrochloride
CAS No.	21801-94-5
Molecular Formula	C5H12ClNO
Molecular Weight	137.61 g/mol
Synonyms	(S)-2-(Aminomethyl)tetrahydrofuran hydrochloride; (S)-Tetrahydrofurfurylamine hydrochloride; (S)-2-Tetrahydrofurylmethylamine HCl; (S)-THFA hydrochloride; (2S)-2-(Aminomethyl)tetrahydrofuran hydrochloride; (S)-Aminomethyltetrahydrofuran HCl; (S)-2-Furanmethanamine, tetrahydro-, hydrochloride; (S)-Tetrahydro-2-furancarboxamine hydrochloride
EINECS	Contact for details

Quality Control

Our (2S)-Tetrahydro-2-Furanmethanamine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity assessment by HPLC, to ensure compliance with high-grade standards suitable for research and synthesis. Certificates of Analysis (COA) detailing identity, purity, and specific parameters are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.