Description

1,3-Dioxolane-4-Methanaminium, N,N,N,2-Tetramethyl-, Iodide, (2S-Cis)- is a high-purity, chiral quaternary ammonium salt with a protected diol functionality. This compound serves as a critical advanced pharmaceutical intermediate and a versatile building block in sophisticated organic synthesis. It is essential for research and production in the pharmaceutical, agrochemical, and specialty chemical industries, where its stereochemistry and reactive groups enable the construction of complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the development of active pharmaceutical ingredients (APIs), particularly in neurology and cardiology research.
• Asymmetric Catalysis: Used as a precursor or ligand for chiral phase-transfer catalysts in enantioselective synthesis.
• Agrochemical Synthesis: Building block for creating novel, stereospecific herbicides, fungicides, and plant growth regulators.
• Material Science: Monomer or additive for synthesizing specialized polymers and ionic liquids with unique properties.
• Academic & R&D: Valuable reagent for methodological studies in organic chemistry and medicinal chemistry programs.
• Process Chemistry: Employed in scale-up and optimization for the commercial manufacturing of fine chemicals.

Basic Information

Product Name	1,3-Dioxolane-4-Methanaminium, N,N,N,2-Tetramethyl-, Iodide, (2S-Cis)-
CAS No.	21795-59-5
Molecular Formula	C9H20INO2
Molecular Weight	285.17 g/mol
Synonyms	(2S-cis)-1,3-Dioxolane-4-methanaminium, N,N,N,2-tetramethyl-, iodide; (4R)-2,2-Dimethyl-4-[(trimethylammonio)methyl]-1,3-dioxolane iodide; (R)-2,2-Dimethyl-4-((trimethylammonio)methyl)-1,3-dioxolane iodide; (4R)-4-[(Trimethylammonio)methyl]-2,2-dimethyl-1,3-dioxolane iodide; (R)-4-((Trimethylammonio)methyl)-2,2-dimethyl-1,3-dioxolane iodide; (R)-TADDOL-derived quaternary ammonium salt; (4R)-TMA-Dioxolane iodide; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our 1,3-Dioxolane-4-Methanaminium, N,N,N,2-Tetramethyl-, Iodide, (2S-Cis)- is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical and advanced synthetic applications. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, ensuring full traceability and compliance with your internal specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.