Description

1H-Thieno[3,4-D]Imidazole-4-Valeric Acid, Hexahydro-2-Oxo-, Stereoisomer (8Ci) is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure. This compound is of significant commercial importance for its role as a key building block in the synthesis of active pharmaceutical ingredients (APIs) and other fine chemicals. It is primarily sought by research institutions and manufacturers in the pharmaceutical and biotechnology sectors for the development of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of complex drug molecules, particularly those targeting specific enzymatic pathways.
• Active Pharmaceutical Ingredient (API) Synthesis: Serves as a core structural component for constructing APIs with potential neurological or metabolic activity.
• Biochemical Research: Used as a standard or reagent in medicinal chemistry research for studying structure-activity relationships (SAR).
• Process Development: Employed in the scale-up and optimization of synthetic routes for new chemical entities (NCEs) in pilot plants.
• Fine Chemical Production: Utilized in the manufacture of specialized, high-value chemicals for advanced material science applications.

Basic Information

Product Name	1H-Thieno[3,4-D]Imidazole-4-Valeric Acid, Hexahydro-2-Oxo-, Stereoisomer (8Ci)
CAS No.	21788-37-4
Molecular Formula	C11H16N2O3S
Molecular Weight	256.32 g/mol
Synonyms	Hexahydro-2-oxo-1H-thieno[3,4-d]imidazole-4-valeric acid; Stereoisomer of Biotin intermediate; 5-(Hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl)pentanoic acid; Biotin precursor; Thienoimidazole valeric acid; 21788-37-4; (3aS,4S,6aR)-Hexahydro-2-oxo-1H-thieno[3,4-d]imidazole-4-valeric acid (specific isomer); Tetrahydro-2-oxothieno[3,4-d]imidazoline-4-valeric acid
EINECS	Contact for details

Quality Control

Our production of 1H-Thieno[3,4-D]Imidazole-4-Valeric Acid, Hexahydro-2-Oxo-, Stereoisomer (8Ci) adheres to stringent quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral analysis for stereochemical integrity, to ensure compliance with research and pharmaceutical-grade standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed to exclude moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% ee (by Chiral HPLC)
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.