Description

5-Bromo-2-Iodobenzoic Acid is a high-purity halogenated benzoic acid derivative, serving as a critical building block in advanced organic synthesis. Its value lies in providing a versatile, multi-functional scaffold for constructing complex molecules, particularly in pharmaceutical and agrochemical research. This compound is essential for medicinal chemists and process development scientists engaged in creating novel active ingredients, where its distinct halogen atoms enable precise cross-coupling reactions and structural modifications.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for candidates targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the development of novel herbicides and fungicides, leveraging its halogenated structure for bioactivity.
• Ligand and Catalyst Development: Serves as a starting material for synthesizing specialized ligands used in transition metal-catalyzed reactions like Suzuki-Miyaura and Buchwald-Hartwig couplings.
• Material Science Research: Employed in the creation of organic electronic materials and liquid crystals due to its aromatic core and halogen substituents.
• Custom Synthesis and Contract Manufacturing: A fundamental reagent for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for client R&D.
• Academic Research: Utilized in university and institutional labs for methodological development in organic chemistry and heterocycle formation.

Basic Information

Product Name	5-Bromo-2-Iodobenzoic Acid
CAS No.	21740-00-1
Molecular Formula	C7H4BrIO2
Molecular Weight	326.92 g/mol
Synonyms	2-Iodo-5-bromobenzoic Acid; Benzoic acid, 5-bromo-2-iodo-; 5-Bromo-2-iodobenzoic acid; 21740-00-1; 2-Iodo-5-bromobenzoic acid; 5-Bromo-o-iodobenzoic acid; AI3-26070; SCHEMBL118276; CTK8C7241; MolPort-001-785-119; ZINC000005014761; AKOS005259065; AS-81033
EINECS	Contact for details

Quality Control

Our 5-Bromo-2-Iodobenzoic Acid is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR, to ensure it meets the high standards required for synthetic applications. A Certificate of Analysis (COA) detailing batch-specific results is provided with each shipment. We support compliance with relevant regulatory frameworks for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, the container should be opaque or stored in dark conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Melting Point	Contact for details
Heavy Metals	<20 ppm
Residue on Ignition	<0.1%
Water Content (KF)	<0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.