Description

5-Bromo-2-Chlorobenzoic Acid is a high-purity halogenated benzoic acid derivative serving as a critical building block in advanced organic synthesis. Its value lies in providing a multifunctional aromatic core with distinct halogen handles for selective cross-coupling and further functionalization, enabling the creation of complex molecular architectures. This intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of active ingredients and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those targeting central nervous system (CNS) disorders and anti-inflammatory applications.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and plant growth regulators, leveraging its halogenated structure for bioactivity.
• Ligand and Catalyst Development: Serves as a starting material for synthesizing specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Precursor: Employed in the production of advanced polymers, liquid crystals, and organic electronic materials due to its rigid aromatic structure.
• Custom Synthesis and R&D: A versatile scaffold for contract research organizations (CROs) and academic institutions exploring new chemical entities and reaction pathways.

Basic Information

Product Name	5-Bromo-2-Chlorobenzoic Acid
CAS No.	21739-92-4
Molecular Formula	C7H4BrClO2
Molecular Weight	235.46 g/mol
Synonyms	2-Chloro-5-bromobenzoic Acid; 5-Bromo-2-chlorobenzoic acid; Benzoic acid, 5-bromo-2-chloro-; 5-Bromo-o-chlorobenzoic Acid; NSC 403119; BRN 2049405; 2-Chloro-5-bromo-benzoic acid
EINECS	Contact for details

Quality Control

Our 5-Bromo-2-Chlorobenzoic Acid is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis, to ensure it meets the stringent requirements of our global clientele. Certificates of Analysis (COA) with full traceability are provided for all shipments, and we support compliance with REACH and other major regulatory frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect product stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Melting Point	168°C - 172°C
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals (as Pb)	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.