Description

5-Nitro-2H-[1,2,4]Triazole-3-Carboxylic Acid is a high-purity, functionalized heterocyclic building block of significant interest in advanced organic synthesis. Its value lies in its dual functionality, combining a reactive carboxylic acid group with a nitro-substituted triazole core, enabling its use in the construction of complex molecular architectures. This compound is primarily needed by research institutions and industrial R&D departments in the pharmaceutical, agrochemical, and specialty materials sectors for developing novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting infectious diseases or cancer, where the triazole scaffold is pharmacologically relevant.
• Agrochemical Research: Used in the development of new herbicides, fungicides, or insecticides, leveraging its heterocyclic structure for bioactivity.
• Energetic Materials Synthesis: Serves as a building block for the research and development of specialized, nitrogen-rich compounds in controlled applications.
• Coordination Chemistry & Ligand Design: The carboxylic acid and triazole nitrogen atoms can act as donors for creating metal-organic frameworks (MOFs) or catalytic complexes.
• Polymer Modification: Can be incorporated into polymer backbones or used as a functionalizing agent to impart specific chemical properties to advanced materials.
• Chemical Biology & Proteomics: Useful as a tagging or linking agent in bioconjugation chemistry for probe and assay development.

Basic Information

Product Name	5-Nitro-2H-[1,2,4]Triazole-3-Carboxylic Acid
CAS No.	21732-99-0
Molecular Formula	C3H2N4O4
Molecular Weight	158.07 g/mol
Synonyms	5-Nitro-1,2,4-triazole-3-carboxylic acid; 3-Carboxy-5-nitro-1,2,4-triazole; 5-Nitro-1H-1,2,4-triazole-3-carboxylic acid; 5-Nitro-2H-1,2,4-triazole-3-carboxylic acid; 5-Nitro-[1,2,4]triazole-3-carboxylic acid; NTCA; 5-Nitro-3-triazolecarboxylic acid
EINECS	Contact for details

Quality Control

Our 5-Nitro-2H-[1,2,4]Triazole-3-Carboxylic Acid is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay and impurity profiles. Our quality commitment supports your R&D and scale-up processes with reliable, traceable materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere if necessary for long-term storage. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.