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(1S,3S)-2,2,3-Trimethyl-3-(4-Methylphenyl)Cyclopentanol CAS NO 21730-87-0


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CAS No.:21730-87-0

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

(1S,3S)-2,2,3-Trimethyl-3-(4-Methylphenyl)Cyclopentanol is a high-purity, stereochemically defined cyclopentanol derivative that serves as a critical chiral intermediate in advanced organic synthesis. Its precise stereochemistry and functional group make it a valuable building block for creating complex molecules with specific spatial orientations. This compound is primarily utilized by research institutions and industrial R&D departments in the pharmaceutical and agrochemical sectors for the development of novel active ingredients.

Application

  • Pharmaceutical Intermediate: A key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and anti-inflammatory drugs.
  • Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides where specific stereochemistry is required for biological activity.
  • Flavor & Fragrance Chemistry: Serves as a precursor for synthesizing specific musk or woody odorants in high-value perfumery applications.
  • Material Science Research: Employed as a monomer or modifying agent in the development of specialized polymers with tailored properties.
  • Catalyst & Ligand Development: Acts as a backbone structure for creating novel chiral ligands used in asymmetric catalysis.
  • Academic & Contract Research: A valuable reagent for methodological studies in synthetic organic chemistry and stereoselective transformations.

Basic Information

Product Name (1S,3S)-2,2,3-Trimethyl-3-(4-Methylphenyl)Cyclopentanol
CAS No. 21730-87-0
Molecular Formula C₁₅H₂₂O
Molecular Weight 218.33 g/mol
Synonyms (1S,3S)-2,2,3-Trimethyl-3-p-tolylcyclopentanol; (1S-cis)-2,2,3-Trimethyl-3-(4-methylphenyl)cyclopentanol; 3-(4-Methylphenyl)-2,2,3-trimethylcyclopentanol (stereoisomer); Ambroxide precursor intermediate; Cyclopentanol, 2,2,3-trimethyl-3-(4-methylphenyl)-, (1S,3S)-; (-)-Ambrox related alcohol; p-Methylphenyl trimethylcyclopentanol
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Quality Control

Our (1S,3S)-2,2,3-Trimethyl-3-(4-Methylphenyl)Cyclopentanol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure high stereochemical and chemical purity suitable for demanding synthetic applications. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from heat and incompatible materials.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to reference spectrum
Assay (HPLC) ≥ 98.0%
Chiral Purity (Chiral HPLC) ≥ 99.0% (1S,3S isomer)
Loss on Drying ≤ 0.5%
Residue on Ignition ≤ 0.1%
Heavy Metals (as Pb) ≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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