Description

2,3,4A,5,6,7,8,8A-Octahydrospiro[Naphthalene-1(4H),2'-[1,3]Dioxolan]-4-One is a high-purity, specialized spirocyclic ketone compound that serves as a critical synthetic intermediate and building block in advanced organic synthesis. Its unique fused ring structure containing a dioxolane moiety makes it a valuable precursor for constructing complex molecular architectures. This product is essential for research and development chemists in the pharmaceutical, agrochemical, and fine chemical industries seeking to develop novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of complex drug candidates, particularly those with spirocyclic or polycyclic frameworks.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, leveraging its structural complexity.
• Fine Chemical Production: Serves as a versatile precursor for fragrances, flavors, and other specialty chemicals requiring specific stereochemistry.
• Material Science Research: Investigated as a monomer or precursor for novel polymers and organic electronic materials.
• Academic & R&D Laboratories: A valuable reagent for methodological studies in organic chemistry, including cyclization and functional group transformation reactions.
• Catalyst & Ligand Development: Potential scaffold for creating novel chiral ligands or organocatalysts used in asymmetric synthesis.

Basic Information

Product Name	2,3,4A,5,6,7,8,8A-Octahydrospiro[Naphthalene-1(4H),2'-[1,3]Dioxolan]-4-One
CAS No.	21727-93-5
Molecular Formula	C₁₃H₂₀O₃
Molecular Weight	224.30 g/mol
Synonyms	Spiro[1,3-dioxolane-2,1'(4'H)-naphthalen]-4'-one, octahydro-; Octahydrospiro[[1,3]dioxolane-2,1'-naphthalen]-4'-one; 1,4-Dioxaspiro[4.5]decan-8-one, hexahydro-; Hexahydro-1,4-dioxaspiro[4.5]decan-8-one; 21727-93-5; Spirocyclic dioxolane ketone; Octahydrospiro(dioxolane-naphthalen)one
EINECS	Contact for details

Quality Control

Our 2,3,4A,5,6,7,8,8A-Octahydrospiro[Naphthalene-1(4H),2'-[1,3]Dioxolan]-4-One is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and available upon request. We support cGMP and ISO compliant documentation for regulated industry applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed when not in use to prevent moisture absorption and contamination. Store away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.