Description

D-Nva-Ome.Hcl is a high-purity, non-natural amino acid derivative, specifically the methyl ester hydrochloride salt of D-Norvaline. This chiral building block is critical for the synthesis of peptides and peptidomimetics with enhanced metabolic stability and specific biological activity. It is primarily utilized by pharmaceutical R&D and fine chemical synthesis laboratories for developing novel therapeutic agents and bioactive compounds.

Application

• Pharmaceutical Intermediates: A key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for metabolic and neurological targets.
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis (SPPS) to incorporate the D-isomer of norvaline, altering peptide conformation and resistance to enzymatic degradation.
• Biochemical Research: Serves as a standard or reagent in enzymatic studies and metabolic pathway analysis due to its non-proteinogenic nature.
• Proteomics & Diagnostics: Employed in the design and synthesis of specialized peptide probes, substrates, or inhibitors for diagnostic assays and proteomic research.
• Agrochemical Development: Acts as a building block for synthesizing novel, bioactive peptide-like compounds with potential herbicidal or pesticidal properties.
• Academic & Industrial R&D: Fundamental raw material for synthetic chemistry research in universities and corporate labs exploring new chemical entities and material science.

Basic Information

Product Name	D-Nva-Ome.Hcl
CAS No.	21685-17-6
Molecular Formula	C6H14ClNO2
Molecular Weight	167.63 g/mol
Synonyms	D-Norvaline methyl ester hydrochloride; (R)-2-Aminopentanoic acid methyl ester hydrochloride; Methyl (R)-2-aminopentanoate hydrochloride; D-2-Aminovaleric acid methyl ester HCl; H-D-Nva-OMe·HCl; (R)-Methyl 2-aminopentanoate hydrochloride; D-α-Aminovaleric acid methyl ester hydrochloride
EINECS	Contact for details

Quality Control

Our D-Nva-Ome.Hcl is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical research and fine chemical synthesis. A Certificate of Analysis (COA) detailing identity, purity, and specific impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% (D-isomer)
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.