Description

o-2-Propynylhydroxylamine Hydrochloride is a specialized organic building block and reagent of significant interest in advanced synthetic chemistry. Its core value lies in its unique bifunctional structure, incorporating both a reactive propargyl group and a hydroxylamine moiety, which enables its use in the synthesis of complex heterocycles and functionalized molecules. This compound is primarily needed by research and development teams in the pharmaceutical, agrochemical, and material science industries for creating novel molecular entities and developing new synthetic methodologies.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for nitrogen-containing heterocycles.
• Agrochemical Synthesis: Used in the creation of novel herbicides, fungicides, and insecticides that require specific amine or hydroxylamine functional groups.
• Chemical Biology & Bioconjugation: Serves as a versatile linker or functional handle in probe development and protein labeling strategies due to its reactive alkyne group.
• Material Science Research: Employed in the synthesis of specialized polymers, ligands for catalysis, and advanced organic frameworks.
• Academic & Industrial R&D: A valuable reagent for methodological studies in organic synthesis, including cycloaddition reactions and C-N bond formation.

Basic Information

Product Name	o-2-Propynylhydroxylamine Hydrochloride
CAS No.	21663-79-6
Molecular Formula	C₃H₆ClNO
Molecular Weight	107.54 g/mol
Synonyms	O-(2-Propynyl)hydroxylamine hydrochloride; Propargyloxyamine hydrochloride; N-(Prop-2-yn-1-yloxy)amine hydrochloride; 2-Propyn-1-ol, 1-amino-, hydrochloride (9CI); Hydroxylamine, O-2-propynyl-, hydrochloride; O-Propargylhydroxylamine HCl; N-Hydroxypropargylamine hydrochloride
EINECS	Contact for details

Quality Control

Our o-2-Propynylhydroxylamine Hydrochloride is produced under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.