Description

3-Oxetanamine is a versatile and highly valuable heterocyclic building block, specifically a strained four-membered oxetane ring bearing a primary amine functional group. This unique structure makes it a critical intermediate for the synthesis of complex molecules in advanced pharmaceutical and agrochemical research. Its primary application is as a key precursor in the development of novel active pharmaceutical ingredients (APIs), where it is used to introduce the oxetane moiety to modulate physicochemical properties. Industries engaged in medicinal chemistry, process development, and fine chemical manufacturing will find this high-purity intermediate essential for their R&D and production pipelines.

Application

• Pharmaceutical Intermediate: A key building block for synthesizing novel drug candidates, particularly in oncology, antiviral, and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides with improved efficacy and environmental profiles.
• Material Science: Serves as a monomer or cross-linking agent in the production of specialty polymers and advanced functional materials.
• Ligand and Catalyst Development: Employed in the creation of novel chiral ligands and organocatalysts for asymmetric synthesis.
• Bioconjugation Chemistry: Utilized as a reactive handle for linking payloads to antibodies, proteins, or other biomolecules in ADC (Antibody-Drug Conjugate) and probe development.
• Chemical Biology Tool: Acts as a probe or a scaffold for studying biological pathways and protein function.

Basic Information

Product Name	3-Oxetanamine
CAS No.	21635-88-1
Molecular Formula	C3H7NO
Molecular Weight	73.09 g/mol
Synonyms	3-Aminooxetane; Oxetan-3-amine; 3-Oxetanyl amine; 3-Oxetanamine hydrochloride (salt form); Aminomethyl ethylene oxide; Oxacyclobutane-3-amine; 1,3-Epoxy-2-propylamine
EINECS	Contact for details

Quality Control

Our 3-Oxetanamine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for demanding synthetic applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles as determined by advanced analytical techniques. Our quality commitment aligns with cGMP principles where applicable, supporting its use in pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 1.0%
Total Impurities	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.