Description

5-Chloro-2,3-Dihydroquinolin-4(1H)-One is a versatile heterocyclic building block of significant importance in advanced organic synthesis. Its core quinolinone structure, functionalized with a chlorine atom, makes it a critical intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders, anti-infectives, and other therapeutic areas.
• Agrochemical Synthesis: Serves as a building block for developing new herbicides, fungicides, and insecticides, leveraging its heterocyclic core for bioactivity.
• Material Science Research: Used in the development of organic electronic materials, ligands for catalysis, and advanced polymers due to its electron-rich aromatic system.
• Chemical Research & Development: A fundamental starting material for medicinal chemistry programs and structure-activity relationship (SAR) studies in academic and industrial labs.
• Dye and Pigment Intermediate: Can be utilized in the synthesis of specialized quinoline-based dyes and colorants.

Basic Information

Product Name	5-Chloro-2,3-Dihydroquinolin-4(1H)-One
CAS No.	21617-16-3
Molecular Formula	C9H8ClNO
Molecular Weight	181.62 g/mol
Synonyms	5-Chloro-1,2,3,4-tetrahydro-4-oxoquinoline; 5-Chloro-1,2,3,4-tetrahydroquinolin-4-one; 5-Chloro-4-hydroxy-1,2,3,4-tetrahydroquinoline; 4(1H)-Quinolinone, 5-chloro-2,3-dihydro-; 5-Chloro-2,3-dihydro-1H-quinolin-4-one
EINECS	Contact for details

Quality Control

Our 5-Chloro-2,3-Dihydroquinolin-4(1H)-One is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay and impurity profiles. Our quality commitment ensures the material meets the high standards required for research and scale-up applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (typically 15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.