Description

8-Chloro-2,3-dihydroquinolin-4(1H)-one is a versatile and high-value heterocyclic building block, specifically a functionalized dihydroquinolinone derivative. Its core structure makes it a critical intermediate in the synthesis of complex molecules, particularly in the pharmaceutical and agrochemical sectors. This compound is essential for researchers and manufacturers developing active pharmaceutical ingredients (APIs), advanced materials, and fine chemicals, where precise molecular architecture is required.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, anti-inflammatory agents, and antimicrobial compounds.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, leveraging its chlorinated quinoline scaffold.
• Organic Synthesis Building Block: Serves as a versatile starting material for constructing more complex nitrogen-containing heterocycles through various chemical transformations.
• Material Science Research: Investigated for its potential in creating organic electronic materials, ligands for catalysis, and photoluminescent compounds.
• Chemical Research & Development: Employed in academic and industrial R&D labs for method development and exploring new reaction pathways in medicinal chemistry.

Basic Information

Product Name	8-Chloro-2,3-dihydroquinolin-4(1H)-one
CAS No.	21617-11-8
Molecular Formula	C9H8ClNO
Molecular Weight	181.62 g/mol
Synonyms	8-Chloro-1,2,3,4-tetrahydro-4-oxoquinoline; 8-Chloro-1,2,3,4-tetrahydroquinolin-4-one; 8-Chloro-4-hydroxy-1,2,3,4-tetrahydroquinoline; 8-Chloro-3,4-dihydro-2H-quinolin-4-one; 8-Chloro-4-quinolinone, 1,2,3,4-tetrahydro-; 21617-11-8
EINECS	Contact for details

Quality Control

Our 8-Chloro-2,3-dihydroquinolin-4(1H)-one is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment ensures the material meets the high standards required for research and cGMP-grade synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.