Description

1,3-Dioxolane, 4-(Chloromethyl)-2,5-Dimethyl-, Stereoisomer (8Ci) is a specialized heterocyclic compound featuring a chloromethyl functional group, making it a versatile chiral building block and reactive intermediate for advanced synthesis. Its value lies in providing a protected aldehyde equivalent and a reactive handle for further functionalization, enabling the construction of complex molecular architectures with high stereochemical control. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and fine chemical industries developing active ingredients, ligands, and novel materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting the central nervous system or requiring specific stereochemistry.
• Agrochemical Synthesis: Used in the production of advanced pesticides, herbicides, and fungicides where the stereochemistry of the molecule is critical for biological activity.
• Ligand and Catalyst Preparation: Serves as a precursor for chiral ligands used in asymmetric catalysis, such as in hydrogenation or cross-coupling reactions.
• Fine Chemical Building Block: Employed in multi-step organic synthesis to introduce protected aldehyde functionalities and chloromethyl groups for further nucleophilic substitution.
• Polymer Modification: Can be used to introduce reactive sites into polymer chains for creating functionalized materials with specific properties.
• Academic and R&D: A valuable reagent for methodological development and exploring new synthetic pathways in organic and medicinal chemistry research.

Basic Information

Item	Detail
Product Name	1,3-Dioxolane, 4-(Chloromethyl)-2,5-Dimethyl-, Stereoisomer (8Ci)
CAS No.	21590-13-6
Molecular Formula	C6H11ClO2
Molecular Weight	150.60 g/mol
Synonyms	4-(Chloromethyl)-2,5-dimethyl-1,3-dioxolane; 2,5-Dimethyl-4-(chloromethyl)-1,3-dioxolane; (Chloromethyl)acetaldehyde dimethyl acetal (cyclic); Acetaldehyde, (chloromethyl)-, cyclic acetal with 2,3-butanediol; 1,3-Dioxolane, 4-(chloromethyl)-2,5-dimethyl-; 21590-13-6
EINECS	Contact for details

Quality Control

Our production of 1,3-Dioxolane, 4-(Chloromethyl)-2,5-Dimethyl-, Stereoisomer (8Ci) adheres to stringent quality protocols to ensure batch-to-batch consistency and high chemical purity suitable for demanding synthetic applications. We employ advanced analytical techniques including GC, HPLC, and NMR to verify identity, purity, and isomeric composition. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment, and we support compliance with relevant regulatory frameworks for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases and incompatible materials. Due to the light-sensitive and reactive chloromethyl group, containers should be kept sealed under an inert atmosphere when not in use to maintain stability and purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Isomeric Purity (Chiral HPLC)	Contact for details
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.