Description

N-(2-Hydroxypropyl)methacrylamide is a versatile bifunctional monomer featuring both a polymerizable methacrylamide group and a reactive hydroxyl group. This unique structure makes it a critical building block for synthesizing advanced functional polymers with tailored properties. It is essential for manufacturers in the biomedical, personal care, and specialty coatings industries seeking to create materials with specific biocompatibility, adhesion, or hydrophilicity characteristics.

Application

• Biomedical Hydrogels & Drug Delivery Systems: A key monomer for creating cross-linked, water-swellable hydrogels used in contact lenses, wound dressings, and controlled-release pharmaceutical carriers.
• Functional Polymer Coatings: Used to synthesize polymers for coatings that require enhanced adhesion, hydrophilicity, or specific surface functionalization for industrial and optical applications.
• Personal Care Polymers: Serves as a modifying agent in hair fixatives, nail polishes, and skincare formulations to improve film-forming properties, flexibility, and moisture retention.
• Chromatography Media & Affinity Supports: Employed in the production of functionalized beads and resins for HPLC columns and protein purification due to its hydroxyl group available for further conjugation.
• Adhesives & Sealants: Imparts improved toughness, flexibility, and chemical resistance when copolymerized into acrylic-based adhesive systems.
• Research & Chemical Synthesis: A valuable intermediate for organic synthesis and academic research in polymer science and material chemistry.

Basic Information

Product Name	N-(2-Hydroxypropyl)methacrylamide
CAS No.	21442-01-3
Molecular Formula	C7H13NO2
Molecular Weight	143.18 g/mol
Synonyms	HPMA; N-(2-Hydroxypropyl)methacrylamide; 1-Hydroxy-2-(methacrylamido)propane; 2-Hydroxypropyl Methacrylamide; Methacrylamide, N-(2-hydroxypropyl)-; N-(2-Hydroxy-1-methylethyl)methacrylamide; N-Methacryloyl-2-hydroxypropylamine
EINECS	244-387-5

Quality Control

Our N-(2-Hydroxypropyl)methacrylamide is produced under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets exacting standards for sensitive applications like biomedical research and polymer synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be kept under an inert atmosphere for long-term storage to prevent polymerization or degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.