Description

3-Chloro-6,7,8,9-Tetrahydro-5H-Benzo[7]Annulen-5-One is a specialized organic building block belonging to the class of functionalized benzannulated ketones. This compound is valued for its unique fused ring structure and reactive carbonyl and chloro functional groups, which make it a versatile intermediate in advanced synthetic chemistry. It is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the research and development of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and anti-inflammatory targets.
• Agrochemical Synthesis: Used in the synthesis of advanced herbicides, fungicides, and plant growth regulators, leveraging its halogenated ring system.
• Material Science Research: Acts as a precursor for the development of organic semiconductors, liquid crystals, and specialty polymers due to its rigid, conjugated backbone.
• Chemical Research & Development: Employed in academic and industrial R&D labs for methodological studies in organic synthesis, including cyclization and cross-coupling reactions.
• Fine Chemical Production: Utilized in the custom synthesis of complex, high-value specialty chemicals for various technological applications.

Basic Information

Product Name	3-Chloro-6,7,8,9-Tetrahydro-5H-Benzo[7]Annulen-5-One
CAS No.	21413-77-4
Molecular Formula	C11H11ClO
Molecular Weight	194.66 g/mol
Synonyms	3-Chloro-5-oxo-6,7,8,9-tetrahydro-5H-benzo[7]annulene; 3-Chloro-5,6,7,8,9,10-hexahydrobenzocyclohepten-5-one; 5H-Benzo[7]annulen-5-one, 3-chloro-6,7,8,9-tetrahydro-; 3-Chlorocyclohepta[b]benzofuran-5(6H)-one (incorrect but sometimes used); 3-Chloro-6,7,8,9-tetrahydro-5H-benzocyclohepten-5-one
EINECS	Contact for details

Quality Control

Our 3-Chloro-6,7,8,9-Tetrahydro-5H-Benzo[7]Annulen-5-One is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, suitable for demanding R&D and scale-up processes. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable to support our clients' regulatory and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.