Description

[6Ar,(-)]-4,5,6,6A,7,8-Hexahydro-2,11,12-Trimethoxy-6-Methylbenzo[6,7]Cyclohepta[1,2,3-Ij]Isoquinoline-1,10-Diol is a complex isoquinoline alkaloid derivative of significant interest in advanced organic synthesis and pharmaceutical research. This compound serves as a critical chiral building block and intermediate for developing novel bioactive molecules. It is primarily required by pharmaceutical R&D laboratories and fine chemical manufacturers focused on creating new therapeutic agents, particularly in the fields of neurology and cardiology.

Application

• Pharmaceutical Intermediate: Key chiral precursor in the synthesis of potential drug candidates targeting neurological and cardiovascular systems.
• Asymmetric Synthesis: Valuable building block for constructing complex natural product analogs and other stereochemically defined molecules.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to explore new pharmacophores and optimize lead compounds.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
• Biochemical Research: Investigated for its interaction with various biological receptors and enzymes in biochemical assays.

Basic Information

Product Name	[6Ar,(-)]-4,5,6,6A,7,8-Hexahydro-2,11,12-Trimethoxy-6-Methylbenzo[6,7]Cyclohepta[1,2,3-Ij]Isoquinoline-1,10-Diol
CAS No.	21305-36-2
Molecular Formula	C22H27NO5
Molecular Weight	385.46 g/mol
Synonyms	(-)-Glaucine; (S)-Glaucine; L-Glaucine; 1,2,9,10-Tetramethoxyaporphine; NSC 343646; Glaucine; 5,6,6a,7-Tetrahydro-1,2,9,10-tetramethoxy-6-methyl-4H-dibenzo[de,g]quinoline; (+)-Glaucine (enantiomer)
EINECS	Contact for details

Quality Control

Our [6Ar,(-)]-4,5,6,6A,7,8-Hexahydro-2,11,12-Trimethoxy-6-Methylbenzo[6,7]Cyclohepta[1,2,3-Ij]Isoquinoline-1,10-Diol is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing including HPLC for purity, chiral analysis, and identity confirmation to ensure it meets the stringent requirements of pharmaceutical development. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting purity, chiral excess, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.