Description

6-(Hydroxymethyl)Benzo(A)Pyrene is a key hydroxymethylated derivative of the polycyclic aromatic hydrocarbon benzo[a]pyrene. This compound matters as a crucial advanced intermediate and reference standard in toxicological and metabolic research. It is primarily needed by research institutions and chemical manufacturers focused on environmental analysis, carcinogenicity studies, and the synthesis of labeled compounds for analytical detection.

Application

• Metabolic Pathway Research: Used as a standard or intermediate to study the metabolic activation pathways of benzo[a]pyrene and its DNA-adduct forming potential.
• Environmental Toxicology: Serves as a critical analytical standard for calibrating equipment and validating methods in the detection and quantification of polycyclic aromatic hydrocarbon (PAH) metabolites in environmental and biological samples.
• Biomarker Development: Employed in the synthesis and development of biomarkers for human exposure monitoring to carcinogenic PAHs.
• Organic Synthesis: Acts as a versatile building block for the preparation of more complex derivatives, including fluorescent probes or conjugates for biochemical assays.
• Pharmaceutical Research: Utilized in investigative studies to understand chemical carcinogenesis and to screen potential chemopreventive agents.
• Quality Control & Assurance: Functions as a high-purity reference material in analytical laboratories to ensure accuracy and compliance in PAH-related testing.

Basic Information

Product Name	6-(Hydroxymethyl)Benzo(A)Pyrene
CAS No.	21247-98-3
Molecular Formula	C₂₁H₁₄O
Molecular Weight	282.34 g/mol
Synonyms	6-(Hydroxymethyl)benzo[a]pyrene; 6-Hydroxymethyl-BaP; 6-HMBaP; Benzo[a]pyren-6-ylmethanol; 6-Methylolbenzo[a]pyrene; 6-Hydroxymethylbenzo(a)pyrene; BaP-6-CH₂OH; 1-Hydroxymethylbenzo[a]pyrene (positional isomer)
EINECS	Contact for details

Quality Control

Our 6-(Hydroxymethyl)Benzo(A)Pyrene is produced and handled under strict quality protocols to ensure batch-to-batch consistency and high purity, essential for research integrity. Each lot undergoes comprehensive analytical characterization using techniques such as HPLC, NMR, and MS. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your compliance and documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). Due to its light-sensitive nature, prolonged exposure to light should be avoided. Keep the container sealed in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	Off-white to pale yellow solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 95.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.