Description

4-Trityl-3-Thiosemicarbazide is a specialized organic compound featuring a trityl-protected thiosemicarbazide functional group, serving as a critical building block and protective group intermediate in advanced synthetic chemistry. Its primary value lies in enabling the controlled synthesis and modification of complex molecules, particularly in pharmaceutical research and fine chemical production. This high-purity intermediate is essential for R&D chemists and process development scientists working in pharmaceutical, agrochemical, and advanced material sectors who require reliable, high-quality reagents for sensitive synthetic pathways.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly those requiring protected functional groups.
• Peptide Chemistry: Used as a protective group reagent for thiosemicarbazide moieties during peptide synthesis and modification.
• Agrochemical Research: Intermediate in the development of new active ingredients for crop protection products.
• Ligand Synthesis: Precursor for creating specialized ligands used in catalysis and metal complexation studies.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological systems.
• Fine Chemical Production: Valuable intermediate for manufacturing high-value, low-volume specialty chemicals.
• Academic & Industrial R&D: Fundamental reagent for methodological development and exploratory synthesis in organic chemistry laboratories.

Basic Information

Product Name	4-Trityl-3-Thiosemicarbazide
CAS No.	21198-26-5
Molecular Formula	C20H19N3S
Molecular Weight	333.45 g/mol
Synonyms	N-Tritylthiosemicarbazide; 1-Trityl-3-thiosemicarbazide; 4-Tritylthiosemicarbazide; Triphenylmethylthiosemicarbazide; (Triphenylmethyl)thiosemicarbazide; Thiosemicarbazide, N-trityl-; 1-(Triphenylmethyl)thiosemicarbazide; NSC 403697
EINECS	Contact for details

Quality Control

Our 4-Trityl-3-Thiosemicarbazide is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for research and production applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards and can provide material tailored to specific project requirements, including custom purity grades.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive and should be stored away from light to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.