Description

6-Bromopicolinic Acid is a versatile brominated heterocyclic building block essential for advanced organic synthesis. This high-purity intermediate is critical for constructing complex molecules in pharmaceutical and agrochemical research and development. It is primarily sought after by R&D chemists and process development scientists in the life sciences sector for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and plant growth regulators.
• Ligand and Catalyst Preparation: Serves as a precursor for picolinamide and picolinic acid derivatives used in metal-organic frameworks (MOFs) and catalytic systems.
• Material Science Research: Employed in the development of organic electronic materials and functional polymers.
• Chemical Biology Probes: Utilized as a building block for creating labeled compounds and molecular probes for biochemical assays.
• Cross-Coupling Reactions: Acts as a substrate in Suzuki, Buchwald-Hartwig, and other palladium-catalyzed cross-coupling reactions to form biaryl structures.

Basic Information

Product Name	6-Bromopicolinic Acid
CAS No.	21190-87-4
Molecular Formula	C6H4BrNO2
Molecular Weight	202.01 g/mol
Synonyms	2-Bromo-6-pyridinecarboxylic Acid; 6-Bromo-2-pyridinecarboxylic Acid; 2-Pyridinecarboxylic Acid, 6-Bromo-; Picolinic Acid, 6-Bromo-; 6-Bromopyridine-2-carboxylic Acid; 2-Carboxy-6-bromopyridine; 6-Bromo-2-picolinic Acid
EINECS	Contact for details

Quality Control

Our 6-Bromopicolinic Acid is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases and incompatible materials. Due to its nature as a strong acid/organic solvent, appropriate chemical handling procedures should be followed.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	185 - 190 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.