Description

5-tert-Butyl-2-Iodophenol is a versatile iodinated phenolic compound that serves as a key synthetic intermediate in advanced organic chemistry. Its molecular structure, featuring both a sterically hindered tert-butyl group and a reactive iodine substituent, makes it particularly valuable for constructing complex molecules and functional materials. This high-purity building block is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop new active ingredients and performance materials.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and anti-inflammatory applications.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and plant growth regulators, where the phenolic and iodine functionalities enable unique modes of action.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in transition metal catalysis, facilitating challenging cross-coupling and other synthetic transformations.
• Polymer and Material Science: Incorporated into polymer backbones or as a functional modifier to impart specific properties like UV stabilization, flame retardancy, or antimicrobial activity to advanced materials.
• Organic Electronic Materials: Investigated as a component in the synthesis of organic semiconductors and charge-transport materials for OLEDs and photovoltaic devices.
• Chemical Research & Development: A valuable reagent for academic and industrial R&D labs exploring new synthetic methodologies and constructing complex molecular architectures.

Basic Information

Product Name	5-tert-Butyl-2-Iodophenol
CAS No.	20942-70-5
Molecular Formula	C10H13IO
Molecular Weight	276.12 g/mol
Synonyms	2-Iodo-5-tert-butylphenol; 5-(1,1-Dimethylethyl)-2-iodophenol; 5-tert-Butyl-2-iodo-1-hydroxybenzene; 2-Hydroxy-4-tert-butyl-1-iodobenzene; Phenol, 5-(1,1-dimethylethyl)-2-iodo-; 4-tert-Butyl-2-iodophenol (common numbering); t-Butyl iodophenol
EINECS	Contact for details

Quality Control

Our 5-tert-Butyl-2-Iodophenol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and spectroscopic identification (NMR, IR), to ensure it meets stringent specifications for use in sensitive synthetic applications. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and consistent high quality.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated place. Recommended storage temperature is 2-8°C for long-term stability. This material is light-sensitive and easily oxidized; avoid exposure to air, moisture, and strong oxidizers.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.