Description

(1R,2R,5R)-2-Isopropyl-5-Methyl-Cyclohexanol is a high-purity, stereochemically defined isomer of menthol, a compound of significant commercial importance. This specific enantiomer is valued for its consistent and potent organoleptic properties, making it a critical ingredient for applications demanding precise sensory profiles. It is essential for manufacturers in the flavor and fragrance, pharmaceutical, and advanced chemical synthesis sectors who require reliable quality and strict stereochemical control.

Application

• Flavor & Fragrance Industry: A key chiral intermediate and cooling agent in premium mint flavors, oral care products (toothpaste, mouthwash), chewing gums, and confectionery.
• Pharmaceutical Synthesis: Used as a chiral building block or active pharmaceutical ingredient (API) intermediate in the production of analgesics, antipruritics, and other therapeutic agents.
• Aromatherapy & Personal Care: Incorporated into topical formulations such as balms, creams, and lotions for its characteristic cooling and soothing sensation.
• Chemical Synthesis: Serves as a versatile chiral auxiliary or starting material in asymmetric synthesis for producing other fine chemicals and specialty compounds.
• Tobacco & E-Liquids: Employed as a flavoring and cooling additive in mentholated tobacco products and vaping formulations.
• Household & Industrial Products: Used in air fresheners, detergents, and cleaning products to impart a fresh, clean minty aroma.

Basic Information

Product Name	(1R,2R,5R)-2-Isopropyl-5-Methyl-Cyclohexanol
CAS No.	20752-34-5
Molecular Formula	C10H20O
Molecular Weight	156.27 g/mol
Synonyms	(-)-Menthol; L-Menthol; (1R,2S,5R)-Menthol; Levomenthol; Peppermint Camphor; 3-p-Menthanol; Hexahydrothymol; Menthol USP; FEMA 2665; NSC 406042
EINECS	244-158-9

Quality Control

Our (1R,2R,5R)-2-Isopropyl-5-Methyl-Cyclohexanol is produced under strict quality management systems. Each batch is tested to ensure compliance with relevant pharmacopeial standards such as USP, EP, BP, and FCC for food and pharmaceutical grades. We provide comprehensive Certificates of Analysis (COA) detailing purity, enantiomeric excess, and impurity profiles to guarantee batch-to-batch consistency and supply reliability for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The product is not hygroscopic under normal storage conditions.

Specification

Item	Specification
Appearance	White crystalline solid or colorless needles
Identification (IR)	Conforms to reference spectrum
Assay (GC)	≥ 99.0%
Enantiomeric Purity (GC)	≥ 99.5% (1R,2S,5R isomer)
Melting Point	42°C - 45°C
Specific Rotation [α]20/D	-49° to -50° (in ethanol)
Heavy Metals (as Pb)	≤ 10 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.