Description

4-Methoxymandelic Acid is a versatile aromatic hydroxy acid derivative that serves as a critical chiral building block and intermediate in advanced organic synthesis. Its value lies in its methoxy-substituted mandelic acid structure, which is pivotal for introducing specific stereochemistry and functional groups into complex molecules. This compound is essential for research and production in the pharmaceutical and fine chemical industries, where it is used to develop active pharmaceutical ingredients (APIs) and specialty chemicals.

Application

• Pharmaceutical Intermediate: Key chiral precursor in the synthesis of various drug candidates and active pharmaceutical ingredients (APIs), particularly those requiring specific enantiomeric purity.
• Asymmetric Synthesis: Employed as a resolving agent or chiral auxiliary in stereoselective reactions to produce enantiomerically pure compounds.
• Fine Chemical Production: Used in the manufacture of specialty chemicals, including advanced ligands for catalysis and complex organic molecules for material science.
• Biochemical Research: Serves as a standard or reagent in metabolic pathway studies and enzymatic reaction research due to its structural similarity to natural substrates.
• Agrochemical Synthesis: Intermediate in the development of certain herbicides and plant growth regulators that utilize phenoxy acid chemistry.
• Cosmetic Ingredient Precursor: Potential starting material for synthesizing certain skin-conditioning agents and antioxidant derivatives.

Basic Information

Product Name	4-Methoxymandelic Acid
CAS No.	20714-90-3
Molecular Formula	C9H10O4
Molecular Weight	182.17 g/mol
Synonyms	(4-Methoxyphenyl)(hydroxy)acetic acid; 4-Methoxy-α-hydroxybenzeneacetic acid; p-Methoxymandelic acid; (4-Methoxyphenyl)glycolic acid; 2-Hydroxy-2-(4-methoxyphenyl)acetic acid; DL-4-Methoxymandelic acid; (±)-4-Methoxymandelic acid
EINECS	Contact for details

Quality Control

Our 4-Methoxymandelic Acid is produced under a strict quality management system. Each batch undergoes rigorous analytical testing to ensure it meets high-purity standards suitable for pharmaceutical and fine chemical applications. Certificates of Analysis (COA) detailing purity, chiral purity (where applicable), and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials such as strong oxidizing agents, strong bases, and strong acids.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	118°C - 122°C
Loss on Drying	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%
Chiral Purity (if applicable)	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.