Description

(R)-4-Methoxymandelic Acid CAS NO 20714-89-0 is a high-purity chiral building block and intermediate of significant importance in asymmetric synthesis. Its value lies in its utility for constructing complex molecules with defined stereochemistry, which is critical for developing active pharmaceutical ingredients (APIs) and advanced materials. This compound is essential for research and production teams in the pharmaceutical, agrochemical, and fine chemical industries who require enantiomerically pure intermediates for chiral synthesis.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of enantiomerically pure drugs, particularly in cardiovascular and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the development of chiral pesticides and herbicides where specific stereochemistry is required for optimal biological activity.
• Asymmetric Catalyst Ligand Precursor: Serves as a starting material for synthesizing chiral ligands used in metal-catalyzed asymmetric reactions.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, flavors, and fragrances that demand high enantiomeric purity.
• Academic & Industrial R&D: A valuable reagent for methodological development in organic chemistry and process chemistry research.
• Reference Standard: Used as a chromatographic standard for quality control and analytical method development in chiral separation techniques.

Basic Information

Product Name	(R)-4-Methoxymandelic Acid
CAS No.	20714-89-0
Molecular Formula	C9H10O4
Molecular Weight	182.17 g/mol
Synonyms	(R)-(-)-4-Methoxymandelic Acid; (R)-2-Hydroxy-2-(4-methoxyphenyl)acetic Acid; D-(-)-4-Methoxymandelic Acid; (R)-α-Hydroxy-4-methoxybenzeneacetic Acid; (R)-O-Methylmandelic Acid; (2R)-2-Hydroxy-2-(4-methoxyphenyl)ethanoic Acid; (R)-4-Methoxy-α-hydroxybenzeneacetic Acid
EINECS	Contact for details

Quality Control

Our (R)-4-Methoxymandelic Acid is produced under a strict quality management system to ensure batch-to-batch consistency and high enantiomeric purity. Each lot undergoes comprehensive analytical testing, including chiral HPLC for enantiomeric excess (ee) determination, NMR for structural confirmation, and standard pharmacopeial tests. Certificates of Analysis (COA) detailing purity, chiral purity, and impurity profiles are provided and available upon request to support your regulatory and R&D needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Melting Point	158 - 162 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.