Description

3-Methoxysulfolane is a high-purity, polar aprotic solvent and versatile chemical intermediate with significant utility in advanced synthesis and material science. Its unique molecular structure, combining a sulfolane core with a methoxy substituent, provides excellent solvating power and thermal stability, making it a valuable alternative to traditional dipolar aprotic solvents. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty polymer industries, where it facilitates challenging reactions and enhances product performance.

Application

• Pharmaceutical Synthesis: Employed as a reaction solvent and intermediate in the production of active pharmaceutical ingredients (APIs), particularly for nucleophilic substitution and cyclization reactions.
• Agrochemical Formulation: Used as a co-solvent and penetration enhancer in pesticide and herbicide formulations to improve efficacy and stability.
• Polymer & Resin Production: Acts as a solvent and processing aid in the synthesis of high-performance polymers, including polyimides and polysulfones.
• Electrolyte Additive: Investigated for use in lithium-ion battery electrolytes to improve ionic conductivity and electrode stability.
• Gas Treating & Separation: Utilized as a specialized solvent in natural gas sweetening and other industrial gas purification processes to remove acidic components.
• Chemical Intermediate: Serves as a key building block for further chemical modifications to create sulfonamide derivatives and other functional molecules.

Basic Information

Product Name	3-Methoxysulfolane
CAS No.	20627-66-1
Molecular Formula	C5H10O3S
Molecular Weight	150.20 g/mol
Synonyms	3-Methoxy-tetrahydrothiophene 1,1-dioxide; Tetrahydro-3-methoxythiophene 1,1-dioxide; 3-Methoxytetrahydrothiophene-1,1-dioxide; 3-Methoxy-sulfolane; Sulfolane, 3-methoxy-; 3-Methoxy-thiolane 1,1-dioxide
EINECS	Contact for details

Quality Control

Our 3-Methoxysulfolane is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including chromatography and spectroscopy, to confirm identity, potency, and impurity profiles. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong acids and oxidizing agents. Recommended storage temperature is 15-25°C. The product is moisture-stable under these conditions.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Refractive Index (n20D)	1.470 - 1.480
Density (20°C)	1.25 - 1.30 g/mL

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.