Description

3-Deoxy-D-Manno-2-Octulosonic Acid, Ammonium Salt is a key biochemical building block and research reagent, specifically the ammonium salt of the bacterial cell wall component KDO (2-keto-3-deoxyoctonate). This compound is essential for studying bacterial lipopolysaccharide (LPS) biosynthesis and related metabolic pathways. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and life science sectors for biochemical research, enzymatic studies, and as a precursor in the synthesis of complex carbohydrates and glycoconjugates.

Application

• Biochemical Research: Critical substrate for studying the enzymes involved in the biosynthesis of bacterial lipopolysaccharides (LPS) and the 3-deoxy-D-manno-oct-2-ulosonic acid (KDO) pathway.
• Glycobiology & Glycoconjugate Synthesis: Serves as a vital precursor and building block for the chemical and enzymatic synthesis of complex oligosaccharides, glycoproteins, and other glycoconjugates.
• Pharmaceutical Development: Used in research targeting novel antibiotics and anti-infective agents that interfere with bacterial cell wall formation, particularly in Gram-negative bacteria.
• Enzymology & Assay Development: Employed as a standard or substrate in enzymatic assays for KDO transferases and other carbohydrate-active enzymes.
• Microbiology & Immunology: A key tool for investigating host-pathogen interactions, immune response to LPS, and the role of core oligosaccharide structures in virulence.
• Diagnostic Reagent Manufacturing: Potential use in the production of diagnostic kits and reagents for detecting bacterial endotoxins or specific carbohydrate antigens.

Basic Information

Product Name	3-Deoxy-D-Manno-2-Octulosonic Acid, Ammonium Salt
CAS No.	20595-77-1
Molecular Formula	C8H15NO8 • xNH3
Molecular Weight	261.21 g/mol (Free acid, anhydrous)
Synonyms	Ammonium 3-Deoxy-D-manno-oct-2-ulosonate; KDO Ammonium Salt; 2-Keto-3-deoxyoctonic Acid Ammonium Salt; 3-Deoxy-D-manno-oct-2-ulosonic Acid Ammonium Salt; D-3-Deoxy-manno-octulosonic Acid Ammonium Salt; Ammonium 3-Deoxy-D-manno-2-octulopyranosonate; (4R,5R,6S,7S)-4,5,6,7-Tetrahydroxy-2-oxooctanoic Acid Ammonium Salt
EINECS	Contact for details

Quality Control

Our 3-Deoxy-D-Manno-2-Octulosonic Acid, Ammonium Salt is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing to ensure high purity, identity, and consistency, meeting the exacting standards required for research and development. Certificates of Analysis (COA) detailing purity (by HPLC/NMR), identity confirmation, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent absorption of atmospheric moisture, which may affect stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0 %
Specific Rotation	Contact for details
Heavy Metals	< 20 ppm
Residue on Ignition	< 0.5 %
Bacterial Endotoxins	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.