Description

4-(tert-Butoxycarbonyl)Benzoic Acid is a versatile and high-purity chemical intermediate, also known as 4-Boc-benzoic acid. Its primary value lies in its role as a key protected building block for the synthesis of more complex molecules, particularly in pharmaceutical research and development. This compound is essential for chemists and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality intermediates for peptide coupling and other organic synthesis applications.

Application

• Pharmaceutical Intermediate: A crucial protected precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for compounds containing benzoic acid moieties.
• Peptide Synthesis: Used as a Boc-protected amino acid derivative for solid-phase and solution-phase peptide coupling reactions.
• Agrochemical Research: Serves as a building block for developing novel herbicides, fungicides, and plant growth regulators.
• Liquid Crystal & Polymer Chemistry: An intermediate in the production of monomers for advanced polymers and liquid crystal materials.
• Organic Synthesis Reagent: Employed in various organic transformations where a protected carboxylic acid group is required.
• Chemical Reference Standard: Used as a high-purity standard in analytical laboratories for method development and quality control.

Basic Information

Product Name	4-(tert-Butoxycarbonyl)Benzoic Acid
CAS No.	20576-82-3
Molecular Formula	C12H14O4
Molecular Weight	222.24 g/mol
Synonyms	4-Boc-benzoic Acid; 4-(Boc)benzoic Acid; 4-Carboxybenzoic Acid tert-Butyl Ester; Benzoic acid, 4-[(1,1-dimethylethoxy)carbonyl]-; 4-(tert-Butoxycarbonyl)benzoic Acid; 4-tert-Butoxycarbonylbenzoic Acid; p-(tert-Butoxycarbonyl)benzoic Acid; 4-(BOC)Benzoic Acid
EINECS	Contact for details

Quality Control

Our 4-(tert-Butoxycarbonyl)Benzoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and production. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Melting Point	158°C - 162°C
Loss on Drying	≤0.5%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.