Description

3-Chloropropionic Anhydride is a versatile and reactive chemical intermediate essential for introducing the 3-chloropropionyl moiety into target molecules. Its high reactivity makes it a valuable building block for the synthesis of pharmaceuticals, agrochemicals, and specialty polymers. This compound is particularly sought after by R&D chemists and process development teams in the fine chemical and pharmaceutical industries for creating active pharmaceutical ingredients (APIs) and advanced materials.

Application

• Pharmaceutical Intermediate: Key reagent in the synthesis of various active pharmaceutical ingredients (APIs), including β-blockers and other cardiovascular drugs.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and plant growth regulators.
• Polymer Modification: Acts as a monomer or cross-linking agent for producing specialty polymers with specific functional properties.
• Peptide Chemistry: Employed as an acylating agent for the protection or modification of amino acids and peptides.
• Dye and Pigment Manufacturing: Serves as an intermediate in the synthesis of complex organic dyes and colorants.
• Organic Synthesis Reagent: A fundamental building block for laboratory-scale and industrial-scale organic synthesis, facilitating carbon-chain elongation and functional group introduction.

Basic Information

Product Name	3-Chloropropionic Anhydride
CAS No.	20495-99-2
Molecular Formula	C6H8Cl2O3
Molecular Weight	199.03 g/mol
Synonyms	3-Chloropropanoic Anhydride; β-Chloropropionic Anhydride; 3-Chloropropionyl Anhydride; Propanoic Acid, 3-Chloro-, Anhydride; NSC 66495; Bis(3-chloropropionyl) Oxide
EINECS	243-875-1

Quality Control

Our 3-Chloropropionic Anhydride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including assay (by titration), identity confirmation (IR), and impurity profiling (GC/HPLC), to ensure it meets the high-purity standards required for sensitive synthetic applications. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and consistent quality for your critical processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent degradation from atmospheric moisture. Keep away from strong bases, oxidizing agents, and sources of ignition.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Assay (Titration)	≥ 98.0 %
Water Content (KF)	≤ 0.5 %
Free Acid (as 3-Chloropropionic Acid)	≤ 1.0 %

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.