Description

6-Bromo-4-Hydroxy-2-Phenylquinoline is a versatile brominated quinoline derivative that serves as a critical building block in advanced organic synthesis. Its unique molecular structure, featuring both a bromine substituent and a phenolic hydroxyl group, makes it a valuable intermediate for constructing complex heterocyclic systems. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly those targeting neurological disorders, cancer, and infectious diseases.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the bioactivity of the quinoline scaffold.
• Material Science: Serves as a monomer or functional unit in the creation of organic semiconductors, luminescent materials, and metal-organic frameworks (MOFs).
• Chemical Synthesis: Acts as a versatile reagent for Suzuki-Miyaura and other cross-coupling reactions, enabling the introduction of the phenylquinoline moiety into more complex molecules.
• Dye and Pigment Industry: Utilized as an intermediate for synthesizing specialized quinoline-based dyes and colorants.
• Academic & R&D: Employed in universities and corporate labs for methodological studies in heterocyclic chemistry and as a standard for analytical purposes.

Basic Information

Item	Details
Product Name	6-Bromo-4-Hydroxy-2-Phenylquinoline
CAS No.	20364-59-4
Molecular Formula	C15H10BrNO
Molecular Weight	300.15 g/mol
Synonyms	4-Hydroxy-6-bromo-2-phenylquinoline; 2-Phenyl-6-bromo-4-quinolinol; 6-Bromo-2-phenyl-4-quinolinol; 6-Bromo-4-hydroxy-2-phenylquinoline; 4-Quinolinol, 6-bromo-2-phenyl-; 6-Bromo-4-quinolinol, 2-phenyl-; 20364-59-4 (CAS)
EINECS	Contact for details

Quality Control

Our 6-Bromo-4-Hydroxy-2-Phenylquinoline is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals. We provide a Certificate of Analysis (COA) with every shipment to ensure full traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat and incompatible materials. The product is light-sensitive and should be handled accordingly.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.