Description

N1-[4-(tert-Butyl)Phenyl]-2-Chloroacetamide is a specialized organic intermediate featuring a chloroacetamide group linked to a tert-butyl substituted aromatic ring. This molecular structure makes it a valuable building block for the synthesis of more complex chemical entities, particularly in pharmaceutical and agrochemical research. It is primarily sought after by R&D chemists and process development scientists in the fine chemical and life science industries for constructing novel compounds with potential biological activity.

Application

• Pharmaceutical Intermediate: Key synthetic precursor in the research and development of new active pharmaceutical ingredients (APIs), particularly those targeting central nervous system or inflammatory pathways.
• Agrochemical Synthesis: Used as a building block for creating novel herbicides, fungicides, or plant growth regulators, leveraging the reactivity of the chloroacetamide moiety.
• Organic Synthesis Reagent: Serves as an electrophilic agent in amidation and alkylation reactions for introducing the N-(4-tert-butylphenyl)acetamide scaffold into target molecules.
• Chemical Research: Employed in academic and industrial laboratories for methodological studies and the development of new synthetic routes to complex amides and anilides.
• Material Science Precursor: Potential intermediate in the synthesis of specialty polymers or ligands for catalysts where the bulky tert-butyl group provides steric control.

Basic Information

Product Name	N1-[4-(tert-Butyl)Phenyl]-2-Chloroacetamide
CAS No.	20330-46-5
Molecular Formula	C12H16ClNO
Molecular Weight	225.72 g/mol
Synonyms	2-Chloro-N-[4-(1,1-dimethylethyl)phenyl]acetamide; N-(4-tert-Butylphenyl)chloroacetamide; 4-tert-Butylphenylchloroacetamide; p-tert-Butylphenylchloroacetamide; 2-Chloro-N-(4-tert-butylphenyl)acetamide; N-(4-(tert-Butyl)phenyl)-2-chloroacetamide; 2-Chloroacetamide, N-[4-(1,1-dimethylethyl)phenyl]-
EINECS	Contact for details

Quality Control

Our N1-[4-(tert-Butyl)Phenyl]-2-Chloroacetamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) documenting all critical quality parameters are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.