Description

(4Ar,12R)-2,3,4,4Aβ,5,6-Hexahydro-12-Methyl-1H-5β,10Bβ-Propano-1,7-Phenanthroline is a complex, stereochemically defined heterocyclic compound that serves as a critical chiral intermediate in advanced organic synthesis. Its unique fused-ring structure and defined stereochemistry make it invaluable for constructing sophisticated molecular architectures with high precision. This compound is primarily sought by research institutions and pharmaceutical development teams working on novel active pharmaceutical ingredients (APIs), complex natural product analogs, and specialized ligands for catalysis.

Application

• Pharmaceutical Intermediate: A key chiral building block in the synthesis of novel therapeutic agents, particularly in central nervous system (CNS) and anti-infective drug discovery.
• Asymmetric Catalysis: Used as a precursor for developing novel chiral ligands or organocatalysts in enantioselective synthesis.
• Academic & Industrial Research: Serves as a model compound or starting material for methodological studies in organic chemistry and total synthesis projects.
• Fine Chemical Production: Employed in the multi-step synthesis of high-value, complex fine chemicals and specialty materials.
• Reference Standard: Utilized as an analytical standard for quality control and method development in laboratories characterizing related compounds.

Basic Information

Product Name	(4Ar,12R)-2,3,4,4Aβ,5,6-Hexahydro-12-Methyl-1H-5β,10Bβ-Propano-1,7-Phenanthroline
CAS No.	20316-18-1
Molecular Formula	C17H22N2
Molecular Weight	254.37 g/mol
Synonyms	(4aR,12R)-2,3,4,4a,5,6-Hexahydro-12-methyl-1H-5,10b-methano-1,7-phenanthroline; 12-Methyl-1,5-methano-1,7-phenanthroline derivative; 20316-18-1; Propano-1,7-phenanthroline; Hexahydro-12-methyl-1H-5,10b-propano-1,7-phenanthroline; (4aR,12R)-Hexahydro-12-methyl-1H-5,10b-methano-1,7-phenanthroline
EINECS	Contact for details

Quality Control

Every batch of (4Ar,12R)-2,3,4,4Aβ,5,6-Hexahydro-12-Methyl-1H-5β,10Bβ-Propano-1,7-Phenanthroline is manufactured and tested under strict quality management systems. We provide comprehensive analytical data to ensure identity, purity, and consistency, meeting the stringent requirements of research and development applications. A detailed Certificate of Analysis (COA) including chiral purity assessment is available for each lot upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.