Description

Chloroacetylaminoacetonitrile is a versatile bifunctional chemical intermediate featuring both a reactive chloroacetyl group and a nitrile moiety. This unique structure makes it a valuable building block for the synthesis of more complex heterocyclic compounds and active pharmaceutical ingredients (APIs). It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing new molecular entities and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of various heterocyclic compounds, including imidazoles, thiazoles, and oxazoles, which are core structures in many drug molecules.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and plant growth regulators, leveraging its reactivity to create novel active ingredients.
• Peptide Mimetic Research: Serves as a building block for creating peptide analogs and enzyme inhibitors due to the reactivity of the chloroacetyl group with nucleophiles.
• Dye and Pigment Manufacturing: Acts as an intermediate in the synthesis of specialized dyes and colorants for industrial applications.
• Cross-linking Agent: Potential use in polymer chemistry and material science for creating cross-linked networks or functionalized surfaces.
• Chemical Research & Development: A valuable reagent for academic and industrial R&D labs exploring new synthetic pathways and novel chemical entities.

Basic Information

Product Name	Chloroacetylaminoacetonitrile
CAS No.	20301-57-9
Molecular Formula	C4H5ClN2O
Molecular Weight	132.55 g/mol
Synonyms	2-Chloro-N-(cyanomethyl)acetamide; N-(Cyanomethyl)-2-chloroacetamide; Chloroacetamidoacetonitrile; Acetonitrile, [(2-chloroacetyl)amino]-; Glycine, N-(cyanomethyl)-, N-chloroacetyl derivative; Chloroacetylaminomethyl cyanide; α-Chloroacetylaminoacetonitrile; 2-Chloroacetamidoacetonitrile
EINECS	243-726-1

Quality Control

Our Chloroacetylaminoacetonitrile is produced under a strict quality management system. Every batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, impurity profile, and physical characteristics. Our quality commitment ensures the material meets the stringent requirements for use in pharmaceutical and advanced synthetic applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong bases, strong oxidizing agents, and sources of ignition. For long-term storage, consider under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	108°C - 112°C
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.