Description

2-(4-Bromobutyl)-2-Methyl-1,3-Dioxolane is a versatile brominated acetal derivative, serving as a crucial protected aldehyde synthon and alkylating agent in advanced organic synthesis. Its value lies in its bifunctional reactivity, where the bromobutyl chain facilitates nucleophilic substitution while the dioxolane group provides a masked carbonyl functionality, enabling complex, multi-step transformations. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and specialty chemical industries who require high-purity intermediates for constructing complex molecular architectures, such as active pharmaceutical ingredients (APIs) and liquid crystal materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of complex drug molecules, particularly those requiring the introduction of a protected aldehyde or a four-carbon spacer with a terminal halogen for further functionalization.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides where its reactive sites allow for the construction of specific side chains or heterocyclic cores.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for synthesizing mesogenic units and charge-transporting materials in display and lighting technologies.
• Polymer & Resin Modification: Acts as a functional monomer or cross-linking agent to introduce reactive bromine or latent aldehyde groups into polymer backbones.
• Organic Synthesis Reagent: A valuable reagent in academic and industrial R&D for nucleophilic alkylation reactions and as a precursor to 5-bromopentanal equivalents under mild acidic conditions.
• Flavor & Fragrance Chemistry: Employed in the synthesis of specific aroma chemicals that utilize its masked carbonyl functionality for controlled release or specific molecular geometry.

Basic Information

Product Name	2-(4-Bromobutyl)-2-Methyl-1,3-Dioxolane
CAS No.	20210-14-4
Molecular Formula	C8H15BrO2
Molecular Weight	223.11 g/mol
Synonyms	4-Bromo-1-(2-methyl-1,3-dioxolan-2-yl)butane; 2-Methyl-2-(4-bromobutyl)-1,3-dioxolane; 1,3-Dioxolane, 2-(4-bromobutyl)-2-methyl-; 5-Bromopentanal ethylene acetal; 2-(4-Bromobutyl)-2-methyl-[1,3]dioxolane; Bromobutyl methyl dioxolane; Protected 5-bromopentanal
EINECS	Contact for details

Quality Control

Our 2-(4-Bromobutyl)-2-Methyl-1,3-Dioxolane is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high chemical purity suitable for demanding synthetic applications. We provide comprehensive analytical data, including HPLC/GC purity, identity confirmation (IR, NMR), and impurity profiling. A detailed Certificate of Analysis (COA) is supplied with each batch, documenting compliance with our stringent internal specifications. For customers requiring material for GMP-regulated applications, please contact us to discuss custom synthesis and documentation packages.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. The container should be kept tightly sealed to prevent moisture absorption and potential decomposition.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Refractive Index (n20D)	1.470 - 1.480
Density (g/mL, 20°C)	1.30 - 1.35

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.