Description

2-Chloro-7-Methoxyquinazolin-4(3H)-One is a high-purity, versatile quinazolinone derivative serving as a critical building block in advanced organic synthesis. This compound is valued for its reactive chloro and carbonyl groups, which enable precise molecular modifications. It is primarily sought by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in the development of new herbicides and fungicides, leveraging the quinazolinone scaffold's bioactivity.
• Material Science: Serves as a monomer or functional additive in the research of advanced polymers and organic electronic materials.
• Academic & R&D: Employed in medicinal chemistry labs for structure-activity relationship (SAR) studies and library synthesis.
• Chemical Synthesis: Acts as a versatile scaffold for further functionalization to create a diverse array of quinazolinone-based compounds.

Basic Information

Product Name	2-Chloro-7-Methoxyquinazolin-4(3H)-One
CAS No.	20197-98-2
Molecular Formula	C9H7ClN2O2
Molecular Weight	210.62 g/mol
Synonyms	2-Chloro-7-methoxy-4(3H)-quinazolinone; 7-Methoxy-2-chloroquinazolin-4(3H)-one; 2-Chloro-7-methoxyquinazolin-4-ol; 4-Hydroxy-2-chloro-7-methoxyquinazoline; 20197-98-2; 2-Chloro-7-methoxy-3,4-dihydroquinazolin-4-one
EINECS	Contact for details

Quality Control

Our 2-Chloro-7-Methoxyquinazolin-4(3H)-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Impurity (HPLC)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.