Description

4-(2-Bromo-Acetyl)-Benzoic Acid is a versatile and high-purity brominated aromatic ketone-carboxylic acid building block essential for advanced organic synthesis. This compound is critical for introducing specific molecular functionality in the development of complex, high-value chemical entities. It is primarily sought after by research institutions and industrial R&D departments in the pharmaceutical, agrochemical, and material science sectors for constructing novel molecules and intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring a bromoacetyl or benzoic acid moiety.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and plant growth regulators.
• Ligand and Catalyst Development: Serves as a building block for creating specialized ligands used in transition metal catalysis and molecular recognition.
• Polymer and Material Science: Employed in the synthesis of functional monomers for advanced polymers, liquid crystals, and organic electronic materials.
• Cross-coupling Reactions: The bromine atom makes it a suitable substrate for various palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck).
• Peptidomimetics and Bioconjugation: Useful for the site-specific modification of peptides, proteins, and other biomolecules.

Basic Information

Product Name	4-(2-Bromo-Acetyl)-Benzoic Acid
CAS No.	20099-90-5
Molecular Formula	C9H7BrO3
Molecular Weight	243.06 g/mol
Synonyms	4-(Bromoacetyl)benzoic acid; 2-Bromo-1-(4-carboxyphenyl)ethanone; p-(Bromoacetyl)benzoic acid; 4-Carboxy-α-bromoacetophenone; 4-Carboxyphenacyl bromide; α-Bromo-4-carboxyacetophenone; 1-(4-Carboxyphenyl)-2-bromoethanone; 20099-90-5
EINECS	Contact for details

Quality Control

Our 4-(2-Bromo-Acetyl)-Benzoic Acid is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and industrial synthesis. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality system is designed to meet the stringent requirements of our global customer base in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and away from direct light to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	158 - 162 °C
Loss on Drying	≤ 1.0 %
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.