Description

1,2-o-Isopropylidene-α-D-Xylofuranose is a protected sugar derivative, a key chiral intermediate in organic synthesis. Its value lies in providing a stable, non-reactive scaffold for the controlled functionalization of the xylose sugar ring, enabling the synthesis of complex molecules. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries developing nucleoside analogs, glycosidase inhibitors, and other bioactive compounds.

Application

• Pharmaceutical Intermediate: Critical starting material for the synthesis of nucleoside analogs and antiviral/antitumor agents.
• Chiral Building Block: Used in asymmetric synthesis to introduce stereochemistry into complex molecules for agrochemicals and specialty chemicals.
• Glycochemistry Research: Serves as a protected precursor for the study and synthesis of xylose-containing oligosaccharides and glycoconjugates.
• Fine Chemical Synthesis: Employed in the production of flavours, fragrances, and advanced materials requiring specific sugar motifs.
• Biochemical Tool Development: Used to create probes and inhibitors for studying carbohydrate-processing enzymes.

Basic Information

Product Name	1,2-o-Isopropylidene-α-D-Xylofuranose
CAS No.	20031-21-4
Molecular Formula	C8H14O5
Molecular Weight	190.19 g/mol
Synonyms	1,2-O-Isopropylidene-α-D-xylofuranose; 1,2-O-(1-Methylethylidene)-α-D-xylofuranose; α-D-Xylofuranose, 1,2-O-(1-methylethylidene)-; Isopropylidene xylofuranose; 1,2-O-Isopropylidene-D-xylofuranose; Acetonide of D-xylose; D-Xylose acetonide
EINECS	Contact for details

Quality Control

Our 1,2-o-Isopropylidene-α-D-Xylofuranose is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification and impurity profiling by HPLC, to ensure it meets the exacting standards required for advanced synthetic applications. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider using a desiccator or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Optical Rotation [α]20/D	-40° to -44° (c=1 in H2O)
Chiral Purity (HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.