Description

1-Chloro-2,3-Indoledione is a versatile and reactive halogenated indole derivative, serving as a critical synthetic intermediate in advanced organic chemistry. Its unique structure makes it a valuable precursor for constructing complex heterocyclic systems, particularly in the development of novel active pharmaceutical ingredients (APIs) and functional dyes. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop new molecules with targeted biological or photophysical properties.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of indole-based drug candidates, including kinase inhibitors and receptor modulators.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and plant growth regulators with indole scaffolds.
• Dye and Pigment Synthesis: Serves as a precursor for creating specialized indole-derived colorants and fluorescent markers.
• Material Science: Employed in the research of organic semiconductors and conductive polymers due to its electron-accepting properties.
• Biochemical Probes: Utilized in the design of molecular probes and sensors for biological imaging and diagnostics.
• Academic & R&D: A fundamental reagent in university and industrial research laboratories for methodological studies and new reaction development.

Basic Information

Product Name	1-Chloro-2,3-Indoledione
CAS No.	2959-03-7
Molecular Formula	C8H4ClNO2
Molecular Weight	181.58 g/mol
Synonyms	1-Chloroisatin; 1-Chloro-1H-indole-2,3-dione; 1-Chloroindole-2,3-dione; 1-Chloro-2,3-dioxoindoline; Isatin, 1-chloro-; 1-Chloro-2,3-indolinedione; Chloroisatin
EINECS	220-983-6

Quality Control

Our 1-Chloro-2,3-Indoledione is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical data, including HPLC purity, identity confirmation (IR, NMR), and impurity profiling. A Certificate of Analysis (COA) is supplied with each shipment, detailing all relevant specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most critical synthesis steps.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong bases and reducing agents. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.