Description

3-(2-Chloro-Ethyl)-3H-Quinazolin-4-One is a versatile quinazolinone derivative, a key heterocyclic building block prized for its reactive chloroethyl side chain. This compound matters for its role as a critical intermediate in the synthesis of more complex molecules, particularly in pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing novel active compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders, oncology, and inflammation.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides, leveraging the quinazolinone core's bioactivity.
• Fine Chemical Synthesis: Serves as a versatile building block for creating complex heterocyclic compounds in custom synthesis and material science.
• Biochemical Tool Compound: Employed in academic and industrial research to study enzyme inhibition and receptor-ligand interactions.
• Library Synthesis for HTS: A valuable scaffold for generating diverse compound libraries used in high-throughput screening (HTS) campaigns.

Basic Information

Product Name	3-(2-Chloro-Ethyl)-3H-Quinazolin-4-One
CAS No.	2940-68-3
Molecular Formula	C₁₀H₉ClN₂O
Molecular Weight	208.65 g/mol
Synonyms	3-(2-Chloroethyl)-4(3H)-quinazolinone; 3-(2-Chloroethyl)quinazolin-4(3H)-one; 4(3H)-Quinazolinone, 3-(2-chloroethyl)-; 3-(β-Chloroethyl)-4-hydroxyquinazoline; Quinazolin-4(3H)-one, 3-(2-chloroethyl)-; 2940-68-3; NSC 51194
EINECS	220-937-4

Quality Control

Our 3-(2-Chloro-Ethyl)-3H-Quinazolin-4-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, impurity profile, and physical characteristics. Our quality commitment supports your R&D and scale-up processes with reliable, traceable material.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider storage under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.