Description

3-Fluoro-8-Quinolinesulfonyl Chloride is a high-purity, reactive sulfonyl chloride derivative used as a critical building block in advanced organic synthesis. This compound matters for its role in introducing the sulfonamide functional group, a key moiety in the development of active pharmaceutical ingredients and specialty chemicals. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and material science industries for creating novel molecules with targeted properties.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of sulfonamide-based drug candidates, including potential enzyme inhibitors and receptor antagonists.
• Agrochemical Research: Used to develop novel herbicides, fungicides, and pesticides by constructing bioactive sulfonamide cores.
• Material Science: Serves as a monomer or cross-linking agent in the creation of functional polymers and advanced materials.
• Chemical Biology Probes: Employed in the design and synthesis of activity-based probes for studying enzyme function and protein labeling.
• Dye and Pigment Synthesis: Acts as an intermediate in the production of specialized quinoline-based dyes and colorants.
• Custom Synthesis & Contract Manufacturing: Supplied for bespoke organic synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	3-Fluoro-8-Quinolinesulfonyl Chloride
CAS No.	2925-55-5
Molecular Formula	C9H5ClFNO2S
Molecular Weight	245.66 g/mol
Synonyms	8-Quinolinesulfonyl chloride, 3-fluoro-; 3-Fluoroquinoline-8-sulfonyl chloride; 3-Fluoro-8-quinolinesulphonyl chloride; 2925-55-5; 3-Fluoroquinoline-8-sulfonylchloride; 3-Fluoro-8-sulfonylchloride quinoline; 3-Fluoro-8-quinoline sulfonyl chloride
EINECS	Contact for details

Quality Control

Our 3-Fluoro-8-Quinolinesulfonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and FTIR, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are available upon request, supporting compliance with research and cGMP guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.