Description

3-Chloro-4-Fluoroacetophenone is a versatile and high-purity organic intermediate characterized by its distinct halogenated aromatic ketone structure. This compound is critical for the synthesis of complex molecules, offering precise reactivity for introducing specific functional groups. It is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those requiring halogenated aromatic motifs for bioactivity.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides, where the chloro-fluoro substitution pattern enhances efficacy and environmental stability.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for creating specialized organic electronic compounds used in display technologies.
• Organic Synthesis & Research: Employed in academic and industrial R&D for constructing complex heterocycles and as a reagent in Friedel-Crafts and other coupling reactions.
• Dye & Pigment Intermediate: Utilized in the manufacture of specialized dyes and pigments where halogen atoms influence color fastness and spectral properties.

Basic Information

Product Name	3-Chloro-4-Fluoroacetophenone
CAS No.	2923-66-2
Molecular Formula	C8H6ClFO
Molecular Weight	172.58 g/mol
Synonyms	1-(3-Chloro-4-fluorophenyl)ethanone; 3'-Chloro-4'-fluoroacetophenone; 3-Chloro-4-fluorophenyl methyl ketone; 4-Fluoro-3-chloroacetophenone; 3-Chloro-4-fluoroacetophenone; 3-Chloro-4'-fluoroacetophenone; 3-Chloro-4-fluorophenylethanone; Acetophenone, 3-chloro-4-fluoro-
EINECS	220-880-1

Quality Control

Our 3-Chloro-4-Fluoroacetophenone is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistency. We provide detailed Certificates of Analysis (COA) with each shipment, confirming compliance with customer specifications and relevant industry standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat sources and incompatible materials. The container should be kept tightly sealed to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	48 - 52 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.