Description

[5-(4-Amino-2-Oxo-Pyrimidin-1-Yl)-3,4-Dihydroxy-Oxolan-2-Yl]Methoxy-[Hydroxy-[3,4,5-Trihydroxy-6-(Hydroxymethyl)Oxan-2-Yl]Oxy-Phosphoryl]Oxy-Phosphinic Acid is a complex nucleotide derivative of significant biochemical interest. This compound matters as a key intermediate in the synthesis of modified nucleosides and nucleotides, which are crucial for research in molecular biology, virology, and medicinal chemistry. It is primarily needed by pharmaceutical R&D teams, biotechnology companies, and academic research institutions focused on developing novel antiviral agents, enzyme inhibitors, and probes for nucleic acid research.

Application

• Pharmaceutical Intermediate: Critical building block for the synthesis of novel nucleoside analog drugs targeting viral polymerases.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies, particularly those involving kinases, polymerases, and other nucleotide-processing enzymes.
• Antiviral Agent Development: Serves as a precursor in the research and development of potential therapeutics for viral infections.
• Probe Synthesis: Utilized to create labeled or modified nucleotides for diagnostic assays and molecular imaging.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies to optimize the potency and selectivity of nucleotide-based compounds.
• Enzyme Mechanism Studies: Acts as a tool compound to investigate the catalytic mechanisms and binding sites of nucleic acid-metabolizing enzymes.

Basic Information

Product Name	[5-(4-Amino-2-Oxo-Pyrimidin-1-Yl)-3,4-Dihydroxy-Oxolan-2-Yl]Methoxy-[Hydroxy-[3,4,5-Trihydroxy-6-(Hydroxymethyl)Oxan-2-Yl]Oxy-Phosphoryl]Oxy-Phosphinic Acid
CAS No.	2906-23-2
Molecular Formula	C14H23N3O16P2
Molecular Weight	527.29 g/mol
Synonyms	5'-O-Phosphono-5'-deoxyadenosine; Adenosine 5'-(dihydrogen phosphate); 5'-Deoxy-5'-phosphonoadenosine; 5'-Deoxyadenosine 5'-phosphonate; 5'-Phosphonoadenosine; 5'-Adenylic acid analogue; 5'-AMP analogue; 5'-Deoxy-5'-phosphono-A
EINECS	Contact for details

Quality Control

Our [5-(4-Amino-2-Oxo-Pyrimidin-1-Yl)-3,4-Dihydroxy-Oxolan-2-Yl]Methoxy-[Hydroxy-[3,4,5-Trihydroxy-6-(Hydroxymethyl)Oxan-2-Yl]Oxy-Phosphoryl]Oxy-Phosphinic Acid is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) with detailed chromatographic data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry, inert environment. This product is hygroscopic (moisture-sensitive) and light-sensitive. For long-term storage, keep desiccated under an inert atmosphere such as argon or nitrogen.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.