Description

2-[(S)-4-Amino-1,4-Dioxo-2-[[(Benzyloxy)Carbonyl]Amino]Butyl]Hydrazine-1-Carboxylic Acid tert-Butyl Ester is a sophisticated, high-purity chemical building block designed for advanced synthetic applications. Its value lies in its role as a key protected intermediate, enabling the precise construction of complex peptide and hydrazide-based molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and biotechnology sectors, particularly in the development of novel active pharmaceutical ingredients (APIs) and specialized biochemical probes.

Application

• Pharmaceutical Intermediate: A critical building block in the multi-step synthesis of peptide-based drugs and therapeutic agents.
• Peptide Chemistry: Used for the controlled introduction of protected amino acid and hydrazide functionalities into peptide chains during solid-phase or solution-phase synthesis.
• API Development: Serves as a key precursor in research and development for novel Active Pharmaceutical Ingredients, especially those targeting specific enzymatic pathways.
• Bioconjugation: Facilitates the site-specific labeling and modification of proteins, antibodies, and other biomolecules for diagnostic and research purposes.
• Chemical Biology Probes: Employed in the synthesis of specialized probes used to study enzyme function, protein-protein interactions, and cellular processes.
• Custom Synthesis: A valuable starting material for contract research and manufacturing organizations (CROs/CMOs) producing bespoke compounds for client projects.

Basic Information

Product Name	2-[(S)-4-Amino-1,4-Dioxo-2-[[(Benzyloxy)Carbonyl]Amino]Butyl]Hydrazine-1-Carboxylic Acid tert-Butyl Ester
CAS No.	2885-47-4
Molecular Formula	C17H24N4O6
Molecular Weight	380.40 g/mol
Synonyms	(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-4-((tert-butoxycarbonyl)amino)butanoic acid (common mis-assignment check); Nα-Z-Nδ-Boc-L-2,4-diaminobutyric acid hydrazide; Z-Dab(Boc)-NHNH2; Nα-Carbobenzoxy-Nδ-tert-butoxycarbonyl-L-2,4-diaminobutyric hydrazide; Boc-Dab(Z)-hydrazide; L-2,4-Diaminobutyric acid, N2-[(phenylmethoxy)carbonyl]-, N4-(1,1-dimethylethoxy)carbonyl]-, hydrazide; Protected L-Dab-OH hydrazide derivative; Fmoc-Dab(Boc)-OH related intermediate (common search term)
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to stringent quality protocols to ensure batch-to-batch consistency and reliability for sensitive synthetic workflows. Certificates of Analysis (COA) are provided with each shipment, detailing key parameters such as purity, chiral purity, and impurity profiles. While not a bulk API, our quality systems are designed to support cGMP principles for pharmaceutical development, and we can provide material suitable for research through to pre-clinical stages.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This material is light-sensitive (store away from light) and may be hygroscopic; ensure containers are sealed under inert atmosphere if specified and opened in a dry environment to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (HPLC)	≥ 99.0% (S-isomer)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.