Description

2-Chloro-4-(Trifluoromethyl)Quinoline is a high-value, multi-functional heterocyclic building block characterized by its unique halogenated and fluorinated structure. This compound is essential for advanced organic synthesis, particularly in the development of complex molecules with tailored electronic and steric properties. It is primarily sought after by R&D chemists and process development teams in the pharmaceutical, agrochemical, and material science industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of quinoline-based drug candidates, including potential kinase inhibitors, antimicrobials, and anti-inflammatory agents.
• Agrochemical Active Ingredient Development: Used in research to create new herbicides, fungicides, and insecticides, leveraging the biological activity of the quinoline core.
• Material Science & Organic Electronics: Serves as a precursor for organic light-emitting diodes (OLEDs), semiconductors, and liquid crystals due to its electron-deficient aromatic system.
• Coordination Chemistry & Ligand Synthesis: The nitrogen and chlorine atoms make it a useful starting point for constructing chelating ligands in catalysis and metal-organic frameworks (MOFs).
• Fluorine Chemistry Research: The trifluoromethyl group provides a stable source of fluorine for studying structure-activity relationships and metabolic stability in bioactive compounds.
• Custom Synthesis & Contract Manufacturing: A critical building block for custom synthesis houses serving the life sciences sector with bespoke chemical entities.

Basic Information

Product Name	2-Chloro-4-(Trifluoromethyl)Quinoline
CAS No.	2806-29-3
Molecular Formula	C10H5ClF3N
Molecular Weight	231.60 g/mol
Synonyms	2-Chloro-4-(trifluoromethyl)quinoline; 4-(Trifluoromethyl)-2-chloroquinoline; Quinoline, 2-chloro-4-(trifluoromethyl)-; 2-Chloro-4-trifluoromethylquinoline; 2-Chloro-α,α,α-trifluoro-4-quinolinemethanol (related); 2806-29-3; 2-Cl-4-CF3-Quinoline
EINECS	Contact for details

Quality Control

Our 2-Chloro-4-(Trifluoromethyl)Quinoline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting all critical quality attributes. Our quality commitment supports applications requiring high-purity intermediates for research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.