Description

3-Deoxy-1,2:5,6-Di-o-Isopropylidene-A-D-Glucofuranose is a protected carbohydrate derivative, specifically a deoxy sugar with isopropylidene acetal groups, serving as a crucial chiral intermediate in organic synthesis. Its value lies in providing a rigid, non-participating framework that enables selective chemical modifications at specific hydroxyl positions, which is essential for constructing complex bioactive molecules. This high-purity building block is primarily needed by research institutions and pharmaceutical companies engaged in the development of nucleoside analogs, antiviral agents, and other fine chemicals where stereochemical control is paramount.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the synthesis of nucleoside and nucleotide analogs with potential antiviral or anticancer activity.
• Glycochemistry Research: Used in the study and preparation of modified sugars and glycomimetics for probing biological pathways.
• Asymmetric Synthesis: Serves as a starting material or auxiliary for constructing stereochemically defined complex molecules in medicinal chemistry.
• Fine Chemical Production: Employed in the multi-step synthesis of specialty chemicals requiring high enantiomeric purity.
• Academic & R&D Laboratories: A valuable tool for methodological development in synthetic organic chemistry and carbohydrate chemistry.

Basic Information

Item	Details
Product Name	3-Deoxy-1,2:5,6-Di-o-Isopropylidene-A-D-Glucofuranose
CAS No.	2774-29-0
Molecular Formula	C₁₂H₂₀O₅
Molecular Weight	244.28 g/mol
Synonyms	3-Deoxy-1,2:5,6-di-O-isopropylidene-α-D-glucofuranose; 3-Deoxy-1,2:5,6-di-O-(1-methylethylidene)-α-D-glucofuranose; 1,2:5,6-Di-O-isopropylidene-3-deoxy-α-D-glucofuranose; 3-Deoxy-1,2:5,6-di-O-isopropylidene-α-D-ribo-hexofuranose; 3-Deoxy-di-O-isopropylidene-α-D-glucofuranose
EINECS	220-479-6

Quality Control

Our 3-Deoxy-1,2:5,6-Di-o-Isopropylidene-A-D-Glucofuranose is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification and impurity profiling, to ensure it meets the high standards required for advanced synthetic applications. Certificates of Analysis (COA) detailing purity, identity, and specific tests are available for every lot upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Optical Rotation	Contact for details
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.