Description

Acetamide, n-(2-Bromophenyl)-2,2,2-Trifluoro- is a specialized trifluoroacetamide derivative featuring a brominated aromatic ring, making it a valuable high-purity building block for advanced chemical synthesis. Its unique molecular structure provides a versatile scaffold for constructing complex molecules in pharmaceutical and agrochemical research. This compound is essential for R&D chemists and process development scientists working on novel active ingredients, particularly in medicinal chemistry where halogen and fluorine substitutions are critical for modulating biological activity and metabolic stability.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, especially for incorporating bromoaryl and trifluoroacetamide pharmacophores.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and insecticides where the bromophenyl group contributes to target specificity.
• Material Science Research: Serves as a precursor for specialty polymers and liquid crystals, leveraging its aromatic and fluorinated components.
• Organic Synthesis Building Block: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and as a protected amine equivalent in multi-step synthetic routes.
• Chemical Reference Standard: Used for analytical method development, calibration, and quality control in laboratories requiring high-purity certified materials.

Basic Information

Product Name	Acetamide, n-(2-Bromophenyl)-2,2,2-Trifluoro-
CAS No.	2727-71-1
Molecular Formula	C8H5BrF3NO
Molecular Weight	268.03 g/mol
Synonyms	N-(2-Bromophenyl)-2,2,2-trifluoroacetamide; 2-Bromo-N-(trifluoroacetyl)aniline; 2',2',2'-Trifluoroacet-o-bromoanilide; 2-Bromophenyltrifluoroacetamide; o-Bromotrifluoroacetanilide; α,α,α-Trifluoro-N-(2-bromophenyl)acetamide; 2-Bromo-α,α,α-trifluoroacetanilide
EINECS	Contact for details

Quality Control

Our Acetamide, n-(2-Bromophenyl)-2,2,2-Trifluoro- is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with agreed specifications. Our quality commitment supports applications in GMP-aligned environments for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (typically 15-25°C). Keep away from strong bases and oxidizing agents. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.