Description

o-Benzylhydroxylamine Hydrochloride is a versatile organic salt widely used as a key building block and protecting group reagent in advanced chemical synthesis. Its primary value lies in its ability to introduce the O-benzylhydroxylamine moiety, which is crucial for constructing oxime ethers and other nitrogen-oxygen functional groups. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries developing active ingredients and novel molecular entities.

Application

• Pharmaceutical Intermediate: A critical reagent in the synthesis of oxime-containing drug candidates, including kinase inhibitors and anti-inflammatory agents.
• Agrochemical Synthesis: Used in the production of herbicides and fungicides that utilize oxime ether functionalities for enhanced biological activity.
• Peptide Chemistry & Bioconjugation: Serves as a valuable linker or protecting group in the modification of peptides and proteins for research and therapeutic applications.
• Material Science: Employed in the development of specialty polymers and functional materials that require specific amine-oxide linkages.
• Organic Synthesis Reagent: Acts as a nucleophile for the preparation of heterocycles, such as isoxazolines and isoxazoles, which are common scaffolds in medicinal chemistry.
• Analytical Chemistry: Can be used as a derivatization agent for the detection and analysis of carbonyl compounds via oxime formation.

Basic Information

Product Name	o-Benzylhydroxylamine Hydrochloride
CAS No.	2687-43-6
Molecular Formula	C7H9NO • HCl
Molecular Weight	159.61 g/mol
Synonyms	O-Benzylhydroxylamine HCl; N-(Benzyloxy)amine Hydrochloride; Benzyloxyamine Hydrochloride; (Benzyloxy)amine Hydrochloride; O-(Phenylmethyl)hydroxylamine Hydrochloride; Hydroxylamine, O-benzyl-, hydrochloride; N-Hydroxy-N-(phenylmethyl)amine Hydrochloride; BnONH2•HCl
EINECS	220-259-6

Quality Control

Our o-Benzylhydroxylamine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and commercial synthesis. Certificates of Analysis (COA) with detailed specifications are provided for every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	158 - 162 °C
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.