Description

Lathosterol Tms is a trimethylsilyl (TMS) ether derivative of lathosterol, a key intermediate in the biosynthesis of cholesterol. This compound, identified by CAS No. 2665-03-4, is a critical analytical standard and synthetic building block for research in lipid metabolism and sterol chemistry. It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and manufacturers of high-purity reference materials for use in gas chromatography-mass spectrometry (GC-MS) analysis and metabolic pathway studies.

Application

• Analytical Reference Standard: Serves as a primary standard for the qualitative and quantitative analysis of sterols and related metabolites via GC-MS and HPLC.
• Biochemical Research: Used as a crucial intermediate in studies investigating the cholesterol biosynthesis pathway, particularly the conversion of lathosterol to cholesterol.
• Pharmaceutical Development: Employed in the synthesis and quality control of novel therapeutic agents targeting lipid disorders and metabolic diseases.
• Diagnostic Reagent Manufacturing: Incorporated into the production of calibrators and controls for in-vitro diagnostic kits measuring sterol levels.
• Metabolomics & Lipidomics: Essential for profiling and identifying sterol metabolites in complex biological samples for research and clinical applications.

Basic Information

Product Name	Lathosterol Tms
CAS No.	2665-03-4
Molecular Formula	C30H54OSi
Molecular Weight	458.85 g/mol
Synonyms	5α-Cholest-7-en-3β-ol, TMS ether; Lathosterol trimethylsilyl ether; (3β)-5α-Cholest-7-en-3-ol trimethylsilyl ether; 5α-Cholest-7-en-3β-yl trimethylsilyl ether; Lathosterol TMS; Lathosterol-TMS; TMS-Lathosterol; 2665-03-4
EINECS	Contact for details

Quality Control

Our Lathosterol Tms is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including chromatographic purity assessment (HPLC/GC) and structural confirmation (NMR, IR), to ensure it meets the high standards required for research and analytical applications. A Certificate of Analysis (COA) detailing purity, identity, and specific test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive). For long-term storage, consider storing under an inert atmosphere to maintain optimal stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC/GC)	≥ 98.0%
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.