Description

4-Nitrohippuric Acid is a specialized nitro-substituted derivative of hippuric acid, serving as a key synthetic intermediate and analytical standard. This compound is valued for its role in organic synthesis and biochemical research, where its defined structure facilitates the development of novel compounds and analytical methods. It is primarily utilized by research institutions, pharmaceutical development labs, and fine chemical manufacturers requiring high-purity building blocks.

Application

• Pharmaceutical Intermediate: Used in the synthesis of more complex active pharmaceutical ingredients (APIs) and drug candidates.
• Biochemical Research: Acts as a substrate or reference standard in enzymatic studies and metabolic pathway investigations.
• Organic Synthesis: Serves as a versatile building block for introducing the nitrohippuryl moiety into target molecules.
• Analytical Chemistry: Employed as a high-purity calibration standard in chromatographic (HPLC) and spectroscopic analysis.
• Chemical Reference Material: Used for method development and validation in quality control laboratories.

Basic Information

Product Name	4-Nitrohippuric Acid
CAS No.	2645-07-0
Molecular Formula	C9H8N2O5
Molecular Weight	224.17 g/mol
Synonyms	N-(4-Nitrobenzoyl)glycine; Hippuric acid, 4-nitro-; 4-Nitrobenzoylaminoacetic acid; p-Nitrohippuric Acid; (4-Nitrobenzamido)acetic acid; Glycine, N-(4-nitrobenzoyl)-; 4-Nitrobenzoylglycine
EINECS	220-158-5

Quality Control

Our 4-Nitrohippuric Acid is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including identification, purity assay, and impurity profiling, to ensure it meets the high standards required for research and synthesis. A Certificate of Analysis (COA) detailing specific results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent absorption of atmospheric moisture.

Specification

Item	Specification
Appearance	Yellow to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.