Description

2-Quinolinethiol is a versatile sulfur-containing heterocyclic compound that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring both a quinoline ring and a reactive thiol group, makes it an invaluable precursor for creating complex molecules with tailored properties. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries, where it is used to develop active ingredients, ligands, and functional polymers.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those with antimicrobial, antiviral, or anticancer activity.
• Agrochemical Synthesis: Building block for creating advanced pesticides, herbicides, and fungicides.
• Catalyst Ligand: Used to prepare metal-chelating ligands for homogeneous catalysis in fine chemical production.
• Polymer Modification: Acts as a chain transfer agent or functional monomer to introduce sulfur groups into polymers, altering their physical and chemical properties.
• Analytical Chemistry: Employed as a derivatization agent or chelating reagent for the detection and quantification of metal ions.
• Corrosion Inhibitor Formulation: A component in specialty formulations designed to protect metals in harsh environments.
• Material Science Research: Used in the development of organic semiconductors, conductive polymers, and other advanced materials.

Basic Information

Product Name	2-Quinolinethiol
CAS No.	2637-37-8
Molecular Formula	C9H7NS
Molecular Weight	161.22 g/mol
Synonyms	2-Mercaptoquinoline; Quinoline-2-thiol; 2-Quinolinyl mercaptan; 2-Sulfanylquinoline; 2-Thiolquinoline; 2-Quinolyl mercaptan; 2-Quinolinethione (tautomer); 2(1H)-Quinolinethione
EINECS	220-144-6

Quality Control

Our 2-Quinolinethiol is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity. We employ advanced analytical techniques, including HPLC, GC, and NMR, to verify identity and quantify impurities. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and specific impurity limits is provided with each shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	158 - 162 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.