Description

4-Bromo-1,2-(Methylenedioxy)Benzene is a versatile halogenated aromatic compound featuring a methylenedioxy functional group, serving as a critical synthetic intermediate in advanced organic chemistry. Its unique structure makes it a valuable precursor for constructing complex molecules, particularly in the development of pharmaceuticals and agrochemicals. This high-purity building block is essential for research and production chemists in the pharmaceutical, agrochemical, and specialty chemical industries seeking reliable and consistent raw materials for their synthesis pipelines.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds with benzodioxole or halogenated aromatic cores.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides, herbicides, and fungicides where the bromine atom and benzodioxole moiety offer specific biological activity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in catalytic processes, including cross-coupling reactions.
• Material Science Research: Employed in the development of organic electronic materials, dyes, and pigments due to its electron-rich aromatic system.
• Organic Synthesis Building Block: Utilized in various name reactions (e.g., Suzuki, Heck couplings) to introduce functionalized aromatic rings into more complex molecular architectures.
• Flavor and Fragrance Industry: Acts as an intermediate for the synthesis of certain aroma chemicals and synthetic musk compounds.

Basic Information

Product Name	4-Bromo-1,2-(Methylenedioxy)Benzene
CAS No.	2635-13-4
Molecular Formula	C7H5BrO2
Molecular Weight	201.02 g/mol
Synonyms	4-Bromo-1,2-methylenedioxybenzene; 4-Bromobenzodioxole; 1-Bromo-3,4-(methylenedioxy)benzene; 4-Bromocatechol methylene ether; 3,4-Methylenedioxybromobenzene; 4-Bromo-1,3-benzodioxole; Piperonyl Bromide (less common, check context); 4-Bromopiperonyl
EINECS	220-138-7

Quality Control

Our 4-Bromo-1,2-(Methylenedioxy)Benzene is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure it meets the high-purity standards required for pharmaceutical and fine chemical synthesis. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	48 - 52 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.